Ovarian and Endometrial Cancer Screening Exams

Getting tested for endometrial and ovarian cancers depends on your chances of getting the disease and is only recommended for women at increased risk.

Having one or more risks for endometrial or ovarian cancer does not mean you will definitely get the disease. It means that you may be more likely to get endometrial or ovarian cancer. Look at the lists below to find out if you are at average or increased risk for endometrial or ovarian cancer.

Average Risk

Women at average risk include those who have:

  • No history of Hereditary Nonpolyposis Colorectal Cancer
  • No history of Hereditary Ovarian Cancer Syndrome

The benefits of testing for women at average risk of endometrial and ovarian cancers have not been proven. Screening is not recommended.

Increased Risk

Women at increased risk have a higher chance of getting endometrial and/or ovarian cancer than those at average risk. Women at increased risk include those who have a history of:

  • Hereditary Nonpolyposis Colorectal Cancer
  • Hereditary Ovarian Cancer Syndrome

If you fit one or more items from the above list, you should consider following one of the screening schedules below.

Hereditary Nonpolyposis Colorectal Cancer, you should:

  • Have an endometrial biopsy every year beginning at age 35

Hereditary Ovarian Cancer Syndrome, you should:

  • Have a pelvic exam every six to 12 months
  • Get a CA-125 blood test every six to 12 months
  • Ask your health care provider about a transvaginal ultrasound every six to 12 months

These guidelines are for women without any ovarian cancer or endometrial cancer symptoms. If you have any symptoms, you should see your health care provider as soon as possible.

These screening guidelines apply to women who are expected to live for at least another 10 years. The guidelines are not for women who have a health condition that would make it hard for a health care provider to diagnose treat endometrial or ovarian cancer.